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Bioinformatics & Structural Biochemistry Department

Systems Biology of Aging

The Systems Biology of Aging Group was founded by Dr. Robi Tacutu in 2016, and is part of the department of Bioinformatics and Structural Biochemistry at the Institute of Biochemistry of the Romanian Academy. The group is currently funded by a recently awarded EUR 1.9 million grant (Romanian/EU co-funded) for the project “Multi-omics Prediction System for Prioritization of Gerontological Interventions”.

The main areas of interest in the group include studying biology of ageing/biogerontology, systems biology and bioinformatics, overall the expertise required to acheive these spanning multiple research fields (from bioinformatics to synthetic biology).

With a highly multi-disciplinary team, the projects tackeled by the group include both computational aspects (data aggregation and processing, multi-dimensional data analysis, network-based methods, systems theory approaches, deep learning, etc.) as well as wet-lab experiments (in particular in-vivo testing of the computationally predicted interventions).

 

Robi Tacutu, Ph.D.
Robi Tacutu, Ph.D.

Group leader

A thorough, analytical and curiosity-driven scientist, with a multidisciplinary background in biology and computer science, Robi received his BSc in computer science from the University Politehnica Bucharest, and his MSc in biochemistry and molecular biology from the University of Bucharest. He has a long-term commitment and interest in the field of biogerontology (since 2005) and received his PhD in 2013 from the Ben-Gurion University of the Negev, in the lab of Prof. Vadim Fraifeld. His thesis was on an ageing-related topic: studying the relationships between aging and age-related diseases with the use of bioinformatics and network biology approaches, and More...

Alexandra Voinea, Mrs.
Alexandra Voinea, Mrs.

PhD student, Bioinformatics research assistant

Alexandra is a bioinformatics researcher at the Institute of Biochemistry, focussing on developing large screen analysis pipelines and automated tools for data and dataset annotation. She is also a PHD candidate at Univers More...

Anton Yurievich Kulaga, M.Phil.
Anton Yurievich Kulaga, M.Phil.

Bioinformatics research assistant

Anton has a formal background in international management and economics (Kyiv National Economic University, 2003 - 2008, M.A. with honors). Being passionate about programming since high school, he worked for many years as More...

Catalin-Florentin Ion
Catalin-Florentin Ion

Technician, Front-end developer

With a B.Sc. in Communication Sciences, biochim joined the Computational Biology of Aging Group in order to aesthetically shape all of our web resources and interactions with the outside work. Aside from his formal educati More...

Constantina Filipciuc, Mrs.
Constantina Filipciuc, Mrs.

Project Manager

Without managerial help, our projects would surely fail, being swamped at the first sight of bureaucracy. Since Constantina (Tatiana for us) joined the Computational Biology of Aging Group, we have been able to properly fo More...

Costin Chiru, Ph.D.
Costin Chiru, Ph.D.

PhD. Eng. Costin-Gabriel Chiru (200+ citations, h-index 8) is an Associate Professor at the Faculty of Automatic Control and Computers from University Politehnica of Bucharest. In the past, he worked as a Teaching Assistan More...

Dan Mihaila, Mr.
Dan Mihaila, Mr.

Research assistant, Web developer

Dan Mihaila is a researcher in the Institute of Biochemistry of the Romanian Academy. Dan is currently working in Systems Biology of Aging in the Bioinformatics & Structural Biochemistry.

Dmitri Toren
Dmitri Toren

Assistant researcher

Dmitri is a bioinformatics researcher at the Institute of Biochemistry, focusing on curation for aging-related data, analysis of large screen datasets, dataset annotation and network-based analyses. He is also a Ph.D. cand More...

Eugen Ursu, Mr.
Eugen Ursu, Mr.

Junior Bioinformatician

Eugen Ursu is a researcher in the Institute of Biochemistry of the Romanian Academy. Eugen is currently working in Systems Biology of Aging in the Bioinformatics & Structural Biochemistry.

Gabriela Bunu, Mrs.
Gabriela Bunu, Mrs.

PhD student, Bioinformatics research assistant

Gabriela is a bioinformatics researcher at the Institute of Biochemistry, focussing on curation for aging-related data, analysis of large screen datasets and network-based analyses. She has a multidisciplinary background, More...

Ioan Valentin Matei, M.D., Ph.D.
Ioan Valentin Matei, M.D., Ph.D.

Assistant Researcher

Ioan has a background in regenerative medicine, cell therapies, stem cell science and diabetes research. He has worked extensively on endocrine pancreatic cell differentiation, starting with his Ph.D. at the Nippon Dental More...

Laurentiu Spiridon, Dr.
Laurentiu Spiridon, Dr.

Laurentiu Spiridon is a researcher in the Institute of Biochemistry of the Romanian Academy. Laurentiu is currently working in Bioinformatics & Structural Biochemistry in the Bioinformatics & Structural Biochemistry.

Simona Ghenea, Dr.
Simona Ghenea, Dr.

Researcher

Simona Ghenea is a researcher in the Institute of Biochemistry of the Romanian Academy. Simona is currently working in Molecular Cell Biology in the Molecular Cell Biology.

Teodora Bucaciuc
Teodora Bucaciuc

Teodora Bucaciuc is a researcher in the Institute of Biochemistry of the Romanian Academy. Teodora is currently working in Systems Biology of Aging in the Bioinformatics & Structural Biochemistry.

Vlad Constantinescu, Mr.
Vlad Constantinescu, Mr.

PhD student, Machine learning research assistant

Vlad is a senior software engineer (with more than 12 years experience), who has been involved in commercial projects for various partners in the EU, USA, Canada, and having a variety of roles in design, engineering and re More...

Year
Gerontomics: Multi-omics prediction system for prioritization of gerontological interventions 2016-2021
Acronym: Gerontomics
Project director: Robi Tacutu

Starting 02.09.2016, the Institute of Biochemistry of the Romanian Academy is implementing the project “Multi-omics prediction system for prioritization of gerontological interventions”, co-funded through European Fund for Regional Development, in accordance with the funding contract signed by the Ministry of National Education and Scientific Research. The total funding for the project is 8.524.757,50 lei, of which 8.502.557,50 lei represent non-reimbursable funding. The project’s duration is 48 months.

Microsoft Azure Research sponsorship 2017-2018
Acronym: ML for Aging Research
Project director: Robi Tacutu

The Systems Biology of Aging team is grateful for the "Microsoft Azure for Research" sponsorship awarded to our group. We have received cloud computing resources worth the equivalent of 20,000$ credits, and this has greatly helped us to speed up some of our research projects.