Robi Tacutu, Ph.D.
Group: Systems Biology of AgingDepartment: Bioinformatics & Structural Biochemistry
Currently working on
Robi continued his research as a postdoc (2011-2015) at the University of Liverpool, in the Integrative Genomics of Ageing Group, led by Dr. Joao Pedro de Magalhaes. Here, he had a role in developing and curating the Human Ageing Genomic Resources collection of databases relevant to ageing research, and was later awarded a EU FP7 Marie Curie fellowship for developing and interrogating an integrated model of ageing to identify causal relationships between hormonal changes and gene expression changes.
Since 2016, Robi leads the Systems Biology of Aging Group (a group of more than 15 people) at the Institute of Biochemistry and focuses on using computational methods in conjunction with large screening datasets to understand the genetic, cellular, and molecular mechanisms behind ageing, longevity and age-related diseases.
Robi has expertise in Biology of Ageing, Bioinformatics, Systems Biology, Network Biology, and Synthetic Biology.
Human Ageing Genomic Resources: new and updated databases., Nucleic acids research, 46(D1), D1083-D1090, 2018Tacutu R, Thornton D, Johnson E, Budovsky A, Barardo D, Craig T, Diana E, Lehmann G, Toren D, Wang J, Fraifeld VE, de Magalhães JPIF = 11.56000
Wide-scale comparative analysis of longevity genes and interventions., Aging cell, 16(6), 1267-1275, 2017Yanai H, Budovsky A, Barzilay T, Tacutu R, Fraifeld VE
MitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal longevity., Nucleic Acids Res.(44), D1262–D1265, 2015Toren D, Barzilay T, Tacutu R, Lehmann G, Muradian KK, Fraifeld VE.
MicroRNA-regulated protein-protein interaction networks: how could they help in searching for pro-longevity targets?, Rejuvenation research, 13(2-3), 373-7, 2010Tacutu R, Budovsky A, Wolfson M, Fraifeld VE
Starting 02.09.2016, the Institute of Biochemistry of the Romanian Academy is implementing the project “Multi-omics prediction system for prioritization of gerontological interventions”, co-funded through European Fund for Regional Development, in accordance with the funding contract signed by the Ministry of National Education and Scientific Research. The total funding for the project is 8.524.757,50 lei, of which 8.502.557,50 lei represent non-reimbursable funding. The project’s duration is 48 months.