Robi Tacutu, Ph.D.

Currently working on

Biography

Papers

• Ghenea S, Chiritoiu M, Tacutu R, Miranda-Vizuete A, Petrescu SMGhenea S et al . "Targeting EDEM protects against ER stress and improves development and survival in C. elegans", PLoS genetics 18(2): e1010069, (2022)
  IF: 5.90
• Knyazer A, Bunu G, Toren D, Mracica TB, Segev Y, Wolfson M, Muradian KK, Tacutu R, Fraifeld VEKnyazer A et al . "Small molecules for cell reprogramming: a systems biology analysis", Aging 13(24): 25739-25762, (2021)
  IF: 5.68
• Matei IV, Samukange VNC, Bunu G, Toren D, Ghenea S, Tacutu RMatei IV et al . "Knock-down of odr-3 and ife-2 additively extends lifespan and healthspan in C. elegans", Aging 13(undefined), (2021)
  IF: 5.60
• Constantinescu V, Chiru C, Boloni T, Florea A, Tacutu RConstantinescu V et al . "Learning flat representations with artificial neural networks", Applied Intelligence: 2456–2470, (2021)
  IF: 5.09
• Kulaga AY, Ursu E, Toren D, Tyshchenko V, Guinea R, Pushkova M, Fraifeld VE, Tacutu RKulaga AY et al . "Machine Learning Analysis of Longevity-Associated Gene Expression Landscapes in Mammals", International journal of molecular sciences 22(3), (2021)
  IF: 4.56
• Toren D, Yanai H, Abu Taha R, Bunu G, Ursu E, Ziesche R, Tacutu R, Fraifeld VEToren D et al . "Systems biology analysis of lung fibrosis-related genes in the bleomycin mouse model", Scientific reports 11(1): 19269, (2021)
  IF: 4.38AI: 1.28
• Avelar RA, Ortega JG, Tacutu R, Tyler EJ, Bennett D, Binetti P, Budovsky A, Chatsirisupachai K, Johnson E, Murray A, Shields S, Tejada-Martinez D, Thornton D, Fraifeld VE, Bishop CL, de Magalhães JPAvelar RA et al . "A multidimensional systems biology analysis of cellular senescence in aging and disease", Genome biology 21(1): 91, (2020)
  IF: 10.81
• Toren D, Kulaga A, Jethva M, Rubin E, Snezhkina AV, Kudryavtseva AV, Nowicki D, Tacutu R, Moskalev AA, Fraifeld VEToren D et al . "Gray whale transcriptome reveals longevity adaptations associated with DNA repair and ubiquitination", Aging cell 19(7): e13158, (2020)
  IF: 7.24
• Bunu G, Toren D, Ion CF, Barardo D, Sârghie L, Grigore LG, de Magalhães JP, Fraifeld VE, Tacutu RBunu G et al . "SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes", Scientific data 7(1): 366, (2020)
  IF: 5.54
• Bucaciuc Mracica T, Anghel A, Ion CF, Moraru CV, Tacutu R, Lazar GABucaciuc Mracica T et al . "MetaboAge DB: a repository of known ageing-related changes in the human metabolome", Biogerontology 21(6): 763-771, (2020)
  IF: 3.77
• Martin EC, Sukarta OCA, Spiridon L, Grigore LG, Constantinescu V, Tacutu R, Goverse A, Petrescu AJMartin EC et al . "LRRpredictor-A New LRR Motif Detection Method for Irregular Motifs of Plant NLR Proteins Using an Ensemble of Classifiers", Genes (Basel) 11(3): 286, (2020)
  IF: 3.33
• Tacutu R, Thornton D, Johnson E, Budovsky A, Barardo D, Craig T, Diana E, Lehmann G, Toren D, Wang J, Fraifeld VE, de Magalhães JPTacutu R et al . "Human Ageing Genomic Resources: new and updated databases", Nucleic acids research 46(D1): D1083-D1090, (2018)
  IF: 11.15
• Yanai H, Budovsky A, Barzilay T, Tacutu R, Fraifeld VEYanai H et al . "Wide-scale comparative analysis of longevity genes and interventions", Aging cell 16(6): 1267-1275, (2017)
  IF: 7.63
• Toren D, Barzilay T, Tacutu R, Lehmann G, Muradian KK, Fraifeld VEToren D et al . "MitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal longevity", Nucleic acids research 44(D1): D1262-5, (2016)
  IF: 10.16
• Calvert S, Tacutu R, Sharifi S, Teixeira R, Ghosh P, de Magalhães JPCalvert S et al . "A network pharmacology approach reveals new candidate caloric restriction mimetics in C. elegans", Aging cell 15(2): 256-66, (2016)
  IF: 6.71
• Fernandes M, Wan C, Tacutu R, Barardo D, Rajput A, Wang J, Thoppil H, Thornton D, Yang C, Freitas A, de Magalhães JPFernandes M et al . "Systematic analysis of the gerontome reveals links between aging and age-related diseases", Human molecular genetics 25(21): 4804-4818, (2016)
  IF: 5.34
• Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VEYanai H et al . "Tissue repair genes: the TiRe database and its implication for skin wound healing", Oncotarget 7(16): 21145-55, (2016)
  IF: 5.17
• Wood SH, van Dam S, Craig T, Tacutu R, O'Toole A, Merry BJ, de Magalhães JPWood SH et al . "Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging", Genome biology 16: 285, (2015)
  IF: 11.31AI: 6.80
• Craig T, Smelick C, Tacutu R, Wuttke D, Wood SH, Stanley H, Janssens G, Savitskaya E, Moskalev A, Arking R, de Magalhães JPCraig T et al . "The Digital Ageing Atlas: integrating the diversity of age-related changes into a unified resource", Nucleic acids research 43(Database issue): D873-8, (2015)
  IF: 9.20AI: 3.60
• Budovsky A, Craig T, Wang J, Tacutu R, Csordas A, Lourenço J, Fraifeld VE, de Magalhães JPBudovsky A et al . "LongevityMap: a database of human genetic variants associated with longevity", Trends in genetics : TIG 29(10): 559-60, (2013)
  IF: 11.60
• Tacutu R, Craig T, Budovsky A, Wuttke D, Lehmann G, Taranukha D, Costa J, Fraifeld VE, de Magalhães JPTacutu R et al . "Human Ageing Genomic Resources: integrated databases and tools for the biology and genetics of ageing", Nucleic acids research 41(Database issue): D1027-33, (2013)
  IF: 8.81AI: 3.40
• Moskalev AA, Smit-McBride Z, Shaposhnikov MV, Plyusnina EN, Zhavoronkov A, Budovsky A, Tacutu R, Fraifeld VEMoskalev AA et al . "Gadd45 proteins: relevance to aging, longevity and age-related pathologies", Ageing research reviews 11(1): 51-66, (2012)
  IF: 5.95AI: 1.90
• Tacutu R, Shore DE, Budovsky A, de Magalhães JP, Ruvkun G, Fraifeld VE, Curran SPTacutu R et al . "Prediction of C. elegans longevity genes by human and worm longevity networks", PloS one 7(10): e48282, (2012)
  IF: 3.73AI: 1.50
• Tacutu R, Budovsky A, Yanai H, Fraifeld VETacutu R et al . "Molecular links between cellular senescence, longevity and age-related diseases - a systems biology perspective", Aging 3(12): 1178-91, (2011)
  IF: 5.13
• Yanai H, Budovsky A, Tacutu R, Fraifeld VEYanai H et al . "Is rate of skin wound healing associated with aging or longevity phenotype?", Biogerontology 12(6): 591-7, (2011)
  IF: 3.34AI: 0.70
• Tacutu R, Budovsky A, Wolfson M, Fraifeld VETacutu R et al . "MicroRNA-regulated protein-protein interaction networks: how could they help in searching for pro-longevity targets?", Rejuvenation research 13(2-3): 373-7, (2010)
  IF: 4.22AI: 0.60
• Tacutu R, Budovsky A, Fraifeld VETacutu R et al . "The NetAge database: a compendium of networks for longevity, age-related diseases and associated processes", Biogerontology 11(4): 513-22, (2010)
  IF: 3.41AI: 0.80
• Wolfson M, Budovsky A, Tacutu R, Fraifeld VWolfson M et al . "The signaling hubs at the crossroad of longevity and age-related disease networks", The international journal of biochemistry & cell biology 41(3): 516-20, (2009)
  IF: 4.89
• Budovsky A, Tacutu R, Yanai H, Abramovich A, Wolfson M, Fraifeld VBudovsky A et al . "Common gene signature of cancer and longevity", Mechanisms of ageing and development 130(1-2): 33-9, (2009)
  IF: 4.18AI: 1.40
• de Magalhães JP, Lagger C, Tacutu Rde Magalhães JP et al . "Integrative Genomics of Aging", pp 151-171, Handbook of the Biology of Aging, Academic Press, Elsevier, (2021).
  ISBN: 978-0-12-815962-0
• Tacutu R, Toren D, Ursu E, Bunu G, Bucaciuc Mracica TTacutu R et al . "Healthy Biological Systems", pp 53-78, Explaining Health Across the Sciences, Springer, Cham, (2020).
  ISBN: 978-3-030-52662-7
• de Magalhães JP, Tacutu R. "Integrative Genomics of Aging", pp 263-285, Handbook of the Biology of Aging, Elsevier, Academic Press, (2016).
  ISBN: 978-0124115965
• Surleac MD, Spiridon LN, TacutuR, Milac AL, Petrescu SM, Petrescu AJSurleac MD et al . "Structural Assessment of Glycosylation Sites Database - SAGS – An Overall View on N-Glycosylation", pp 3-20, Glycosilation, InTech, (2012).
  ISBN: 978-953-51-0771-2

Grants