Mihaela-Olivia Dobrica, PhD

Biography
Mihaela-Olivia Dobrica is a researcher in the Institute of Biochemistry of the Romanian Academy. Mihaela-Olivia is currently working in Viral Glycoproteins in the Viral Glycoproteins.
Papers
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. "An enrichment protocol and analysis pipeline for long read sequencing of the hepatitis B virus transcriptome", Journal of General Virology 5(104), (2023)
doi: 10.1099/jgv.0.001856
IF: 5.10AI: 1.05 -
. "N-Glycosylation and N-Glycan Processing in HBV Biology and Pathogenesis", Cells 6(9), (2020)
IF: 5.60 -
. "Production of Chimeric Hepatitis B Virus Surface Antigens in Mammalian Cells", Methods in Molecular Biology, Blaine Pfeifer and Andrew Hill (eds.). Springer Science. 2183(Vaccine Delivery Technology: Methods and Protocols), (2020)
Grants
EEA Grants (2014-2021): Next Generation Viral Hepatitis B and C vaccine development in plants and algae using advanced biotechnological tools; ‘’Dezvoltare de vaccinuri de ultima generatie anti Virusurile Hepatice B si C in plante si alge, utilizand metode biotehnologice avansate’’
2019-2023
Acronym: SmartVac
Budget: 1.500.000 EUR
Project director: Norica Nichita
We aim to produce high yields of novel HBV/HCV antigens with superior immunogenic properties in plants and mammalian cells, based on innovative molecular design and establish in premiere an advanced biotechnological platform for production of best vaccine candidates antigens in algae.
Molecular mechanisms of hepatitis B virus egress
2018-2020
Acronym: HBVEGRESS
Project director: Catalin Lazar