Laurentiu Spiridon, Dr.

Biography

Papers

• Șulea TA, Martin EC, Bugeac CA, Bectaș FS, Iacob AL, Spiridon L, Petrescu AJȘulea TA et al . "Lessons from Deep Learning Structural Prediction of Multistate Multidomain Proteins-The Case Study of Coiled-Coil NOD-like Receptors", International journal of molecular sciences 26(2), (2025)
  doi: https://doi.org/10.3390/ijms26020500
  IF: 4.90AI: 1.05
• Chiritoiu G., Munteanu CVA., Sulea TA., Spiridon L., Petrescu AJ., Jandus C., Romero P., Petrescu SM.Chiritoiu G. et al . "Methionine oxidation selectively enhances T cell reactivity against a melanoma antigen", iScience(107205), (2023)
  doi: 10.1016/j.isci.2023.107205
  IF: 6.10AI: 1.63
• Martin EC, Ion CF, Ifrimescu F, Spiridon L, Bakker J, Goverse A, Petrescu AJ.Martin EC et al . "NLRscape: an atlas of plant NLR proteins", Nucleic Acids Res., (2022)
  IF: 19.16AI: 5.51
• Manoliu LCE, Martin EC, Milac AL, Spiridon LManoliu LCE et al . "Effective Use of Empirical Data for Virtual Screening against APJR GPCR Receptor", Molecules (Basel, Switzerland) 26(16), (2021)
  IF: 4.41AI: 0.60
• Spiridon L, Şulea TA, Minh DDL, Petrescu AJ.Spiridon L et al . "Robosample: A Rigid-Body Molecular Simulation Program Based on Robot Mechanics", Biochimica Biophysica Acta General Subjects 1864(8): 129616, (2020)
  IF: 3.68AI: 1.40
• Martin EC, Sukarta OCA, Spiridon L, Grigore LG, Constantinescu V, Tacutu R, Goverse A, Petrescu AJMartin EC et al . "LRRpredictor-A New LRR Motif Detection Method for Irregular Motifs of Plant NLR Proteins Using an Ensemble of Classifiers", Genes (Basel) 11(3): 286, (2020)
  IF: 3.33
• Spiridon L, Minh DDL. "Hamiltonian Monte Carlo with Constrained Molecular Dynamics as Gibbs Sampling", Journal of chemical theory and computation 13(10): 4649-4659, (2017)
  IF: 5.40
• Sueldo DJ, Shimels M, Spiridon LN, Caldararu O, Petrescu AJ, Joosten MH, Tameling WI. et alSueldo DJ et al . "Random Mutagenesis of the Nucleotide-Binding Domain of NRC1 (NB-LRR Required for Hypersensitive Response-Associated Cell Death-1), a Downstream Signalling Nucleotide-Binding, Leucine-Rich Repeat (NB-LRR) Protein, Identifies Gain-Of-Function Mutations in the Nucleotide-Binding Pocket", New Phytologist 208(1): 210-223, (2015)
  IF: 7.43AI: 2.50
• Sela H, Spiridon LN, Ashkenazi H, Bhullar NK, Brunner S, Petrescu AJ, Fahima T, Keller B, Jordan T.Sela H et al . "Three-dimensional Modeling and Diversity Analysis Reveals Distinct AVR Recognition Sites and Evolutionary Pathways in Wild and Domesticated Wheat Pm3 R Genes", Molecular Plant Microbe Interactions 27(8): 835-845, (2014)
  IF: 3.94AI: 1.30
• Ciubotaru M, Trexler AJ, Spiridon LN, Surleac MD, Rhoades E, Petrescu AJ, Schatz DG.Ciubotaru M et al . "RAG and HMGB1 create a large bend in the 23RSS in the V(D)J recombination synaptic complexes", Nucleic Acids Research 41(4): 2437-2454, (2013)
  IF: 8.81AI: 3.40
• Slootweg EJ, Spiridon LN, Roosien J, Butterbach P, Pomp R, Westerhof L, Wilbers R, Bakker E, Bakker J, Petrescu AJ, Smant G, Goverse A.Slootweg EJ et al . "Structural determinants at the interface of the ARC2 and leucine-rich repeat domains control the activation of the plant immune receptors Rx1 and Gpa2", Plant Physiology 162(3): 1510‐1528, (2013)
  IF: 7.39AI: 2.40
• Sela H, Spiridon LN, Petrescu AJ, Akerman M, Mandel-Gutfreund Y, Nevo E, Loutre C, Keller B, Schulman AH, Fahima T.Sela H et al . "Ancient Diversity of Splicing Motifs and Protein Surfaces in the Wild Emmer Wheat (Triticum Dicoccoides) LR10 Coiled Coil (CC) and Leucine-Rich Repeat (LRR) Domains", Molecular Plant Pathology 13(3): 276‐287, (2012)
  IF: 4.49AI: 1.30
• Maekawa T, Cheng W, Spiridon LN, Töller A, Lukasik E, Saijo Y, Liu P, Shen QH, Micluta MA, Somssich IE, Takken FLW, Petrescu AJ, Chai J, Schulze-Lefert PMaekawa T et al . "Coiled-coil domain-dependent homodimerization of intracellular barley immune receptors defines a minimal functional module for triggering cell death", Cell Host Microbe 9(3): 187‐199, (2011)
  IF: 13.50AI: 7.00
• Slootweg E, Roosien J, Spiridon LN, Petrescu AJ, Tameling W, Joosten M, Pomp R, van Schaik C, Dees R, Borst JW, Smant G, Schots A, Bakker J, Goverse A.Slootweg E et al . "Nucleocytoplasmic Distribution Is Required for Activation of Resistance by the Potato NB-LRR Receptor Rx1 and Is Balanced by Its Functional Domains", Plant Cell 22(12): 4195‐4215, (2010)
  IF: 9.40AI: 4.00
• Surleac MD, Spiridon LN, TacutuR, Milac AL, Petrescu SM, Petrescu AJSurleac MD et al . "Structural Assessment of Glycosylation Sites Database - SAGS – An Overall View on N-Glycosylation", pp 3-20, Glycosilation, InTech, (2012).
  ISBN: 978-953-51-0771-2

Grants