Ioana Popa, PhD

Ioana Popa
Group: Molecular Cell Biology
Department: Molecular Cell Biology

CSIII

Research interests: Molecular mechanisms in tumor progression; Role of the receptor for advanced glycation end products (RAGE) and its ligands in cancer

Biography

1998 BSc degree in Biochemistry, Faculty of Biology- University of Bucharest, 2000 MSc degree in Molecular Biology, Faculty of Biology- University of Bucharest 2000-2001 Research assistant- Institute of Biochemistry PhD 2007, Department of Cell Biology, University Medical Center Utrecht, The Netherlands, “Rab4 and its interacting proteins in endosome function” 2007-present Researcher- Institute of Biochemistry Grants received: 1. Intracellular trafficking and signaling properties of the receptor for advanced glycation end produscts (RAGE) under pathological conditions, 2007-2009, Reintegration grant RP-11, contract nr 14/1.10.2007 2. Development of a fluorescence-based technology to screen for RAGE-ligand binding inhibitors, 2017-2018, PN-III-P2-2.1-PED-2016-2000

Papers

Year

Grants

Development of a fluorescence-based technology to screen for RAGE-ligand binding inhibitors 2016-2020
Acronym: FLUORORAGE
Project director: Ioana Popa

The receptor for advanced glycation end-products (RAGE) and its ligands are important players in pathological conditions such as diabetes, neurodegenerative diseases, and cancers. RAGE is a cell surface molecule of the immunoglobulin superfamily. Alternatively spliced variants lacking either only the intracellular domain or both the intracellular and the transmembrane domains are also expressed in some tissues.