Ioana Popa, PhD
2000 MSc degree in Molecular Biology, Faculty of Biology- University of Bucharest
2000-2001 Research assistant- Institute of Biochemistry
PhD 2007, Department of Cell Biology, University Medical Center Utrecht, The Netherlands, “Rab4 and its interacting proteins in endosome function”
2007-present Researcher- Institute of Biochemistry
1. Intracellular trafficking and signaling properties of the receptor for advanced glycation end produscts (RAGE) under pathological conditions, 2007-2009, Reintegration grant RP-11, contract nr 14/1.10.2007
2. Development of a fluorescence-based technology to screen for RAGE-ligand binding inhibitors, 2017-2018, PN-III-P2-2.1-PED-2016-2000
- . Cross-talk between Dopachrome Tautomerase and Caveolin-1 Is Melanoma Cell Phenotype-specific and Potentially Involved in Tumor Progression. The Journal of biological chemistry, 2016, 291(24): 12481-500IF=4.12
- Expression and subcellular localization of RAGE in melanoma cells. Biochemistry and Cell Biology, 2014, 2(92): 127-136 .
- RAGE over AGEs and DAMPs. Romanian Journal of Biochemistry,, 2012, 2(49): 195-210 .
The receptor for advanced glycation end-products (RAGE) and its ligands are important players in pathological conditions such as diabetes, neurodegenerative diseases, and cancers. RAGE is a cell surface molecule of the immunoglobulin superfamily. Alternatively spliced variants lacking either only the intracellular domain or both the intracellular and the transmembrane domains are also expressed in some tissues.