Costin-Ioan Popescu, PhD
Group: Viral GlycoproteinsDepartment: Viral Glycoproteins
Scientific Researcher II
- . A polycarboxylic chelating ligand for efficient resin purification of His-tagged proteins expressed in mammalian systems. RSC Advances, 2020(10): 23931–23935IF=3.04
- Targeting TRAIL. Bioorg Med Chem Lett, 2019, 18(29): 2527-2534 . IF=2.45
Hepatitis C virus (HCV) is an important human pathogen that infects the liver and establishes chronic infection in the majority of cases, leading to cirrhosis and hepatocellular carcinoma over the course of many years. Despite recent progress, details of the HCV life cycle are still missing, with the HCV assembly process being particularly poorly understood.
We aim to produce high yields of novel HBV/HCV antigens with superior immunogenic properties in plants and mammalian cells, based on innovative molecular design and establish in premiere an advanced biotechnological platform for production of best vaccine candidates antigens in algae.