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Structure, Regulation, and Biological Function

Structure, Regulation, and Biological Function 2007-2011
Acronym: PTPNET
Project director: Stefan Szedlacsek
External website: full link

PTPs are proteins with enzymatic properties and a range of cell and tissue functions.

Our overall knowledge about PTP function, however, lags far behind that of many other proteins and PTPNET was therefore established to tackle many pressing questions in the field. These included our desire to understand protein structure and regulation, how PTPs send signals inside cells and tissues, and how PTPs are involved in embryo development and diseases such as cancer, multiple sclerosis and osteoporosis. We also aimed to deliver a comprehensive, internet-based resource for the international research community.

Stefan Szedlacsek, Dr.
Stefan Szedlacsek, Dr.

Head of Department

Professor Dr. Stefan Eugen Szedlacsek is the Head of the Enzymology Department at the Institute of Biochemistry of the Romanian Academy. He holds a PhD degree in Biotechnology from Polytechnic University of Bucharest as well as a MSc in Organic Synthesis (Polytechnic University- Bucharest) and MSc in Mathematics (Bucharest University). As a visiting scientist, he performed research in the field of cholesterol metabolism University of Illinois at Urbana-Champaign (USA), where he succeeded to evidence a new pathway in the metabolism of oxysterols. He is an “Alexander von Humboldt“ fellow and worked in Germany, in the Institute of Biochemistry (Kiel University) More...

Rodica-Aura Badea, Dr.
Rodica-Aura Badea, Dr.

Scientific Researcher

Rodica-Aura Badea is a researcher in the Institute of Biochemistry of the Romanian Academy. Rodica-Aura is currently working in Enzymology in the Enzymology.