Aura-Elena Ionescu, PhD

Aura-Elena Ionescu
Group: Cell Signaling Research
Department: Enzymology

Scientific Researcher

Research interests: G protein-coupled receptors (GPCRs), Signaling pathways in cancer, Mass spectrometry, Protein expression and purification.

Biography

Born: 19th of November 1988, Ploiesti, Romania 2003 - 2007: „Ion Luca Caragiale” National College, Ploieşti, Romania 2007- 2012: Faculty of Pharmacy at University of Medicine and Pharmacy "Carol Davila" Bucharest 2012 - now: Institute of Biochemistry of the Romanian Academy

Papers

Year
  • Balázs Váradi, Károly Brezovcsik, Zoltán Garda, Eniko Madarasi, Horea Szedlacsek, Rodica-Aura Badea, Andrei-Mihai Vasilescu, Adina-Gabriela Puiu, Aura Ionescu, Livia-Elena Sima, Cristian V.A. Munteanu, Simona Călăraș, Adrienn Vagner, Dezső Szikra, Ngô Minh Toàn, Tibor Nagy, Zoltán Szűcs, Stefan Eugen Szedlacsek, Gabor Nagy and Gyula Tircsó.Balázs Váradi et al . "Synthesis and characterization of a novel [52Mn]Mn-labelled affibody based radiotracer for HER2+ targeting", Inorganic Chemistry Frontiers, (2023)
    doi: 10.1039/D3QI00356F
    IF: 7.78AI: 1.01
  • Patras L, Ionescu AE, Munteanu C, Hajdu R, Kosa A, Porfire A, Licarete E, Rauca VF, Sesarman A, Luput L, Bulzu P, Chiroi P, Tranca RA, Meszaros MS, Negrea G, Barbu-Tudoran L, Potara M, Szedlacsek S, Banciu MPatras L et al . "Trojan horse treatment based on PEG-coated extracellular vesicles to deliver doxorubicin to melanoma in vitro and in vivo", Cancer biology & therapy 23(1): 1-16, (2022)
    doi: 10.1080/15384047.2021.2003656
    IF: 4.74
  • Alexandra Manolache, Tudor Selescu, G. Larisa Maier, Mihaela Mentel, Aura Elena Ionescu, Cristian Neacsu, Alexandru Babes, Stefan Eugen SzedlacsekAlexandra Manolache et al . "Regulation of TRPM8 channel activity by Src-mediated tyrosine phosphorylation", Journal of Cellular Physiology 235(6): 5192-5203, (2020)
    IF: 4.52AI: 1.50
  • Ionescu AE, Mentel M, Munteanu CVA, Sima LE, Martin EC, Necula-Petrareanu G, Szedlacsek SEIonescu AE et al . "Analysis of EYA3 Phosphorylation by Src Kinase Identifies Residues Involved in Cell Proliferation", International Journal of Molecular Sciences 20(24): 6307, (2019)
    IF: 4.18
  • Mentel M, Ionescu AE, Puscalau-Girtu I, Helm MS, Badea RA, Rizzoli SO, Szedlacsek SEMentel M et al . "WDR1 is a novel EYA3 substrate and its dephosphorylation induces modifications of the cellular actin cytoskeleton", Scientific reports 8(1): 2910, (2018)
  • Mentel M, Badea RA, Necula-Petrareanu G, Mallikarjuna ST, Ionescu AE, Szedlacsek SEMentel M et al . "Expression, Purification, and Kinetic Analysis of PTP Domains", Methods in molecular biology (Clifton, N.J.) 1447: 39-66, (2016)
  • Petrareanu G, Balasu MC, Vacaru AM, Munteanu CVA, Ionescu AE, Matei I, Szedlacsek SEPetrareanu G et al . "Phosphoketolases from Lactococcus lactis, Leuconostoc mesenteroides and Pseudomonas aeruginosa: Dissimilar sequences, similar substrates but distinct enzymatic characteristics", Applied Microbiology and Biotechnology 18(98): 7855-67, (2014)
    IF: 3.34
  • Ciubotaru M, Trexler AJ, Spiridon LN, Surleac MD, Rhoades E, Petrescu AJ, Schatz DG.Ciubotaru M et al . "RAG and HMGB1 create a large bend in the 23RSS in the V(D)J recombination synaptic complexes", Nucleic Acids Research 41(4): 2437-2454, (2013)
    IF: 8.81AI: 3.40
  • Stefania-Felicia Barbuceanu, Gabriela Bancescu, Gabriel Saramet, Florica Barbuceanu, Constantin Draghici, Flavian Stefan Radulescu, Aura Ionescu, Simona NegresStefania-Felicia Barbuceanu et al . "Synthesis and Biological Evaluation of Some New N1-[4-(4-Chlorophenylsulfonyl) benzoyl]- N4-(aryl)-thiosemicarbazides and Products of Their Cyclization", Synthesis and Biological Evaluation of Some New N -[4-(4-Chlorophenylsulfonyl) benzoyl]- N -(aryl)-thiosemicarbazides and Products of Their Cyclization 24(4): 309-321, (2013)
    doi: DOI 10.1002/hc.21095
    IF: 1.26
  • Mihaela Mentel, Rodica A. Badea, Georgiana Necula - Petrareanu, Sujay T. Mallikarjuna, Aura E. Ionescu, Stefan E. SzedlacsekMihaela Mentel et al . "Expression, Purification, and Kinetic Analysis of PTP Domains", pp 39- 66, Protein Tyrosine Phosphatases, Rafael Pulido, (2016).
    ISBN: 978-1-4939-3744-8
View all papers

Grants

No grants.